Thanks for asking, Sue. We don't typically include artificial sweeteners in our test baking, but we welcome you to try baking this loaf with Splenda if you'd like. For best results, follow the substitution instructions on the package. (If you're using Splenda for Baking, it's typically a 1:1 substitution.) We bet your husband will be quite thankful for your homemade banana bread! Kye@KAF

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